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MEPE has a functional role in the inhibition of chondrocyte ECM mineralization, involving its cleavage, and subsequent phosphorylation, to the ASARM peptide.
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Functional assays suggest that SPARC-like1 may serve as an antagonist to cell adhesion, playing a key role in the inhibition of attachment, and may facilitate spreading of endothelial cells on fibronectin substrates [ 51].
Regulatory T cells (Tregs) play a pivotal role in the inhibition of anti-tumor immune responses.
The decline in K+ concentration may have played an important role in the inhibition of the growth.
The β-carboxyl group of PC plays an important role in the inhibition of cartilage degeneration, little role in the inhibition of FLSs proliferation, and a moderate role in the inhibition of FLSs-mediated calcification.
Despite the morphological similarities, BIns do not act predominantly via perisomatic inhibition like basket cells; therefore, we decided to give them a new name that highlights their unique functional role in layer 4 of the barrel cortex.
These data show that angiogenesis reflected by the serum concentrations of growth factors have a functional role in tumour growth of testicular germ cell cancer and that inhibition of these factors may thus be a promising treatment option.
Facilitatory mechanisms seem to be prevalent in visual adaptation [64, 65]; however, the interplay between excitation and inhibition has important functional role in mechanism of experience-dependent plasticity and deafferentation [66].
Dissecting the functional groups of these compounds, we demonstrated, for the first time to our knowledge, that the vicinal hydroxyl groups of the catechol groups played key functional roles in amyloid inhibition in more than two dozen catechol-containing compounds, including many plant- and fruit-derived flavonoids and other phenolic compounds [2].
This suggests a role for both in the inhibition of motor responses.
Previous findings established an essential role of p27Kip1 in the inhibition of Ras-mediated tumorigenesis [35].
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