Sentence examples for functional replace from inspiring English sources

For example, in human mammary epithelial cells (HMECs), activation of the PI3-kinase pathway in the presence of increased expression of c-myc, can functional replace small T antigen and result in anchorage-independent growth [43].

Alternative members of the community with similar functional characteristics, replace the lost species (Folke et al. 1996; Lee et al. 2010; Barberán et al. 2012).

Over time this surrogate matrix will ideally be replaced by functional replacement tissue.

The same substitution (a functional glycine replaced by a non-functional arginine) in the 219th amino acid of Ehd1 found in T65 rice was also detected (Additional file 3: Figure S2).

The gene editing tool, Crispr, allows scientists to cut, paste and delete single letters of the genome with unprecedented precision, meaning aberrant genes can be overwritten with working copies, and, potentially, functional genes replaced with enhanced versions.

The functional and basal layers are indistinguishable, with the functional layer replaced by an epithelial monolayer unresponsive to hormonal stimulation and fibrotic synechiae forming across the cavity [ 63].

Ugly functional buildings replaced less practical 19th-century palaces; elegant hotels and restaurants made way for airline offices and shopping malls; cars pushed out pedestrians.

This strongly supports the existence of a fundamental take-over in the evolution of the genetic code, in which ancient type II tRNA molecules had their functional identities replaced relatively late in evolution by a modern code.

Increased matrix turnover might be functional in replacing matrix molecules in the repair of a damaged cartilage matrix.

However, an engineered kidney with sufficient functional capacity to replace normal renal function has not yet been developed.

Research accomplishments during the last two decades on cardio-protective drugs or cell-transplantation-mediated therapies, such as stem cells or genetically modified cells, have constituted a revolution in regenerative medicine by creating living and functional tissues to replace damaged tissue or to restore organ function that is lost due to aging, disease and damage [ 16– 20].