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Since propensities in URDME are defined in a program file, any type of functional propensity can be used in URDME models, including Michaelis-Menten and Hill term style propensities, and even arbitrary logical expressions can be employed.
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Since non-coding sequences that are conserved in mammalian evolution are often biologically functional, the propensity of cis-SNPs in the promoter and non-coding regions that are most conserved between mouse and human was examined.
Here we examined the propensity and functional requirement for indels within HIV-1 bnAbs.
Here we examined the propensity and functional requirement for indels within HIV-1 bnAbs.
This article proposes functional networks based on propensity score and Newton Raphson-maximum-likelihood optimizationewas a new large-scale machine learning classifier to enhance its performance in addressing these challenges within big biomedical data.
The propensity of functional changes was reflected in different levels of the gene expression in each cell types.
These observations suggest slower female brain aging, that is, slower age-related functional decline and lower propensity to disease in females.
Impacts of food concentration on freshwater survival differed between the brackish populations, suggesting variation in functional properties affecting their propensity to invade freshwater habitats.
Insertions or deletions of longer sequence elements are expected to have stronger propensities for functional consequences in the protein.
The trade-off between groEL´s high conservation at the sequence and functional levels and its high propensity to evolve novel functions remains poorly understood.
However, in the context of employing amino acid transporter proteins as a means for importing trypanocidal drugs into the parasites, these loci that show less flexibility through time, less propensity for duplication, functional differentiation or loss, could be superior targets since they are less likely to show functional redundancy or sequence variation in the form of tandem duplicates.
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