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Our data demonstrate the morphologic and functional presence of eNOS in the microcirculation.
Recently, however, the functional presence of yet unidentified PACAP receptors have been proposed based on experimental results using selective modulators [15].
The functional presence of eNOS in hcp was investigated by topical application of 10−7 M PAF to the hcp and by measuring NO production by chemiluminescence.
Our study was designed to detect the morphologic and functional presence of eNOS and to test whether eNOS could be phosphorylated by platelet-activating factor (PAF), an agent that induces hyperpermeability.
These results add a further support for the functional presence of TRPM8 channels in human sperm.
Cdc45 and MCMs were enriched at these accumulated forks, suggestive of their functional presence within active forks [69].
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The better reversibility is ascribed to the oxygen functional groups presence that act as catalytic sites reducing kinetic overpotentials.
However, all genomes showed higher functional identity (presence of COGs) reflected by high correlation coefficients among the different genomes (r2 = 0.94), although the distribution of different COGs categories among the different genomes was different and represented the functional diversity.
If proven functional, the presence of a type III secretion system in M. haemolytica will help us re-evaluate our approach to study host-pathogen interactions.
As some of the NICD fragments detected in CRC may not be functional, the presence of γ-secretase-cleaved, active Val1744-NICD fragments was investigated.
In subgroup analyses, the primary endpoint was stratified by baseline sUA, renal functional status, presence of tophi at baseline, and prior participation in a ULT trial [ 13, 14].
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