The average shortest path length and betweenness centrality of functional partners in the clusters are calculated and they are functionally enriched with the Gene Ontology (GO) terms with a p-value cut-off ≤ 0.05.
The presence of distinct but functionally related hemoglobin-degrading enzymes in CQR and CQS pfcrt functional partners is consistent with the interpretation that this functional relationship is preserved in both co-expression networks.
We further observed other biological functions shared by pfcrt partners in both CQR and CQS, including heme biosynthesis and lipoamide biosynthesis, for which distinct but functionally related genes were identified as both CQR and CQS pfcrt functional partners.
Our findings compel consideration of mutations in SLC5A7 or its functional partners in relation to unexplained motor neuronopathies.
We filtered 50 functional partners in NorA, aacA-aphD (aac6ie), aad9ib (ant), aadd (knt), baca (uppP), bl2a_pc (blaZ), ble, ermA, SAV0052 (ermb), ermc, fosB, mecA (mecI), mecR (mecr1), mepA, msrA1, qacA, vraR (str), tet38 and tetM while 40 functional partners are identified in tet and aphA-3 (aph3iiia).
Serve as the lead for the eSTORE organization for cross functional partners acting as a project manager to evaluate, prioritize, develop, manage, implement and test eSTORE initiatives.
For each gene, we detect its nearest functional partners (NFPs).
In a network-embedded model, identifying gene functional partners is the crucial aspect.
A gene always varies in a similar way with their functional partners.
A gene sub-network here is a set of genes that are functional partners to each other.
Second, we introduce the concept of diffusion distance to detect the nearest functional partners (NFPs) of a gene.
