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In a conventional genetic analysis, genes that function in parallel pathways with the same functional output generally demonstrate additive interactions.
Elements of a degenerate system are free to functionally diverge over evolutionary time without compromising the existing functional output.
How T cells "measure" Ag dose and how this determines functional output to a given antigenic dose remain unclear.
The architectural protein CTCF plays a complex role in decoding the functional output of the genome.
"... Here, we use a modeling approach to investigate whether and how the morphology of the basal tree mediates the functional output of neurons.
Facilitating or restricting access to DNA is an ultimate functional output of chromatin, and genome-scale information on DNA inaccessibility is needed for the interpretation of epigenome profiling studies.
Overall, these results reveal a remarkable self-organization of corticofugal and callosal tracts with a functional output, providing new opportunities to examine relevant aspects of human CNS development and disease.
We then tested whether injured cortical axons in the grey matter are able to compensate for the reduced functional output through collateral branching or regeneration of the lesioned axonal stump in the absence of scar tissue (Fig. 4).
The leech heartbeat neural network is famous for its constancy in both architecture and functional output across animals.
Both methods rely on a predictive mathematical framework that maps the enhancer sequence space to functional output.
However, the broader question remains regarding the underlying purpose of mitochondrial dynamics and the translation of these morphological transitions into altered functional output.
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CEO of Professional Science Editing for Scientists @ prosciediting.com