Exact functional opposites were found in the miRNA group that contained the miR-200 families plus miR-7, miR-203, and miR-375.
Finally, PIP2 binding to a similar region has been shown to stabilize the voltage sensor of Kv1 channels in a state of decreased voltage sensitivity, thus promoting functional changes opposite to those described for Kv7 channels51.
Both players will have the same cost functional with opposite sign, and hence, the rewards add up zero, and thus, the game will be zero-sum.
Finally, cells can coordinately express a variety of CCN proteins that are closely related, for example CCN1-3 with cross-over and opposite functional effects yet bearing similar functional domains.
Another main constituent of cannabis, cannabidiol (CBD), has seemingly opposite functional effects on the brain.
Muslims use the same terms that Jews, Christians, Buddhists, and others use, but with significant – even opposite – functional meanings.
Modification of flanking base-pairs with positively or negatively charged functional groups had opposite effects on the orientation of heterodimer binding.
However, an opposite functional interpretation of cross-sectional element ellipticity in which a preferred bending direction is achieved through orientation of Imin has also been proposed specifically for avian wing bones68.
That suggested that DNA polymerase h, when fully functional, generates typos opposite A and T in the antibody genes.
The original pro-survival group includes Bcl2, Bcl-xL, Mcl-1, etc.; an opposite functional group also called pro-apoptotic BH123 protein group includes Bax and Bak; and the third group called apoptosis initiator group is made of BH3 domain-only proteins including Bad, Bid, Bim, Puma, and Noxa (Fig. 1).
