Pseudogenes, defined by the NCBI annotations as non-functional on the basis of evolutionary comparisons, were not included in operons.
Third, for genes with rare variants (i.e., MAF < 5%), we checked whether the number of functional SNPs on the basis of function prediction within gene fragments was greater than or equal to three.
The orthologous clusters were grouped according to function on the basis of functional classification in the arCOG [ 54] database.
Resting-state functional magnetic resonance imaging (rs-fMRI) has enabled the evaluation of brain functional architecture on the basis of blood oxygenation level-dependent (BOLD) signal, which represents the spontaneous neuronal activity at baseline state [ 6].
Unfortunately, so far, there are practically no other "functional" data concerning the HyPRP family (reviewed in Introduction), so we can only speculate on possible functional differences on the basis of HyPRP sequence analyses.
Such a strategy of interchain Staudinger reaction can be extended to construct biosensors for other small functional molecules on the basis of judiciously designed aptamers.
In this review, recent developments and advances of the electrocatalytic ammonia synthesis catalyzed by a series of functional materials on the basis of aforementioned electrolytes have been summarized and discussed, along with the presentation and evaluation of catalyst preparation, reaction parameters and equipment.
The present paper allows us to differentiate these two types of functional hubs on the basis of their structural embedding.
In such circumstances, it is unwise to constrain analysis to functional effects on the basis of prior expectation based on our limited understanding of the action of these agents in other pathologies.
In order to gain insight into the common and differential responses of Mφs and DCs to M. tuberculosis infection, we performed gene functional classification on the basis of the annotation resources provided by GeneOntology (GO) [21] and Kyoto Encyclopedia of Genes and Genomes (KEGG) [22], [23].
Our method provides a prediction of functional profiles on the basis of SILVA-labeled OTU abundances.
