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Orthologs typically retain similar domain architecture and occupy the same functional niche following speciation, while (functionally redundant) paralogs are likely to diverge with new functions through point mutations and domain recombinations [3], [4].
"The leading companies have taken it on in a way that means you don't have to feel like you're self-ghettoized into this functional niche," he said.
The truth is, there are a lot of shows in which certain characters exist solely to carry specific plot threads forward and never really rise above that drab, functional niche.
Therefore, the favored functional niche of LigB may well be early in infection, particularly during cutaneous entry.
These cells a likely to form a functional niche of adult precursor cells with functional relevance in the physiological expansion of the pituitary gland throughout life as well as protection from pituitary disease.
The software explores the functional niche of a species through a series of parameter-flexible models.
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We identified three distinct keratinocyte functional niches: the proliferative niche (narrow geometries), the basement membrane protein synthesis niche (wide geometries) and the putative keratinocyte stem cell niche (narrow geometries and corners).
Additionally, when ecdysone signalling is perturbed during the process of somatic stem cell niche establishment enlarged functional niches able to host additional stem cells are formed.
Thus, replicating a functional HSC niche is important in developing a physiological model of bone metastasis.
Within the bulge region, the MSCs intimately interact with hair follicle stem cells (HFSCs) that are anchored by collagen XVII and provide a functional MSC niche (Fig. 3A).
Erlang is a very niche, functional programming language.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com