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The above is consistent with studies of striated limb muscles that identify hyperelongation of sarcomeres, the functional muscle units, as the primary cause of mechanical muscle injury and resultant muscle dysfunction.
Analysis of the functional muscle-bone unit of the forearm in pediatric renal transplant recipients.
Forming a functional muscle requires the activity of dedicated assembly factors that organize structural and motor proteins into the highly ordered structure of the sarcomere, the basic contractile unit of the muscle.
Making muscle: Embryonic stem cells from mice were used to grow healthy, functional muscle fibers.
Free Flap Functional Muscle Transfers.
Structural-mechanical injuries and functional muscle disorder were included in the acute indirect muscle injury group.
Based on our work in the animal model, we hypothesized that a decline in the maintenance and repair of the muscle functional unit (myofibre maintenance via resident satellite cells) is a main factor causing the lack of old human muscle regeneration, strength and agility.
The functional units of muscle are the half-sarcomeres.
In addition, key organelles such as mitochondria, cell nuclei and their structural constituents were observed revealing the entire structure of the muscle functional units.
Heidersbach et al. observed abnormalities in mitochondria (the cell's energy-producing organelles) as well as dysfunctional sarcomeres the basic functional units of muscle fibres, which consist of thick filaments formed from the protein myosin and thin filaments made up of the protein actin.
The functional unit of muscle contraction is the motor unit.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com