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Specifically, each of four, functional modifying layers (outer polyurethane (PU) selective membrane, the inner selective electropolymer, and the xerogel bi-layer) are systematically investigated and tailored for UA permeability and interferent discrimination.
Taken together, recapitulation of mammalian G85R SOD1 phenotypic and functional modifying effects in C. elegans validates use of the invertebrate ER stress and neuronal models to discern additional mechanistic insights into proteostatic regulation in ALS.
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Some Type I CAD gene knockouts produce a functional modified lignin through the incorporation of cinnamyl aldehyde subunits [22] and perhaps through the overlapping specificities of related gene family members.
This would add significant weight to the argument that ASN is a functional modify of PDF properties.
Density functional theory (DFT) calculations were performed with the plane-wave-pseudo potential package Quantum-ESPRESSO, using ultrasoft pseudopotentials and a PBE-GGA exchange-correlation (xc) functional modified by the self-consistent DF-vdW functional, to account for vdW interactions.
RNA chemical diversity in the RNA world could have been enhanced by the incorporation of catalytic building blocks such as imidazoles, thiols, and amino and carboxylate groups [ 15- 17], or catalytically functional modified nucleotides [ 18, 19].
We selected patients with ischemic stroke on whom we had data on age, pretreatment baseline National Institutes of Health Stroke Scale (b-NIHSS), and 90-day outcome measures (functional modified Rankin score [mRS]) and neurological measures [NIHSS]) in the Virtual International Stroke Trials Archive.
Thus, positive selection might promote functional divergence modifying the binding specificities, or altering the conformational changes involved in the OBP functional mechanism [e.g. [ 14, 45, 46, 51]].
According to the informatics software, this polymorphism had a functional effect modifying the affinity of the sequence by the MZF1 transcription factor.
Based on the advantageous functions of CuONPs and MCs, the functional nanocomposite modified glassy carbon electrode showed high electrocatalytic activity toward the oxidation of glucose.
Primary outcome measure was poor functional outcome (modified Rankin scale score 4-6) after 1 month.
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