Sentence examples for functional linkage of from inspiring English sources
In this respect it is important to note that while functional linkage of USP4 to the TGF-β/SMAD pathway was shown by employing a breast cancer model, USP15 can enhance the tumorigenic effect of TGF-β in glioblastoma (Eichhorn et al., 2012).
This is best explained in terms of a functional linkage of the two hemiretinas, as discussed below.
GAS transcription is regulated through the concerted action of 13 conserved 'two-component' signal transduction systems (named due to the functional linkage of two independent proteins, a sensor kinase and a response regulator) and >60 'stand-alone' transcription factors (named due to their ability to independently regulate transcription) [10], [12].
To verify the functional linkage of these proteins with the ETC we blocked the electron flow of the oxidative phosphorylation chain using piericidin A, a selective inhibitor of NDH (Complex I) [30] where 90% of the membrane potential due to the redox reaction of complex I activity has previously been shown to be inhibited in E. coli [31], [32].
The presumed differing functional linkage of the cytoplasmic SOB Apr lineage I-type APS reductases to the membrane (not involving Qmo complex homologues) was also reflected in the deviating electrostatic potential at the protein surface when compared to the SRB-type AprB models (supplementary data material Figure S1, compare panels E/F).
These likely reflect functional linkage of the encoded proteins.
The domains are highly evolutionarily conserved, and genetic studies in model organisms such as C.elegans, Drosophila, Xenopus laevis, zebrafish, and mice have demonstrated an essential role of ILK in embryonic development and diverse physiological functions, and have confirmed tight functional linkages of ILK with integrins [2], [4].
Functional linkages of general practice with other parts of the health system were addressed in almost all the English plans, but a smaller proportion of other plans.
We wished to determine the functional linkages of genes with AS-NMD as a subpopulation of all genes in an organism.
