Sentence examples for functional knocking from inspiring English sources

We reiterate that protein structural information and more experimental data including functional knocking out assays remains to be obtained from representative members of the four Epd protein groups described here.

Functional knock down of ATG16L1 abrogated autophagy of the intracellular pathogen Salmonella typhimurium [10].

Furthermore, the DNA binding of FOXA2 and HNF6 was investigated in CaCo-2 cells after functional knock down of FOXA2.

As shown in Fig. 5A DNA binding activity of FOXA2 to an optimized FOXA2 oligonucleotide probe was significantly reduced after functional knock down of FOXA2, while in HNF6 plasmid expressing Caco-2 cells FOXA2 DNA binding was significantly increased (see panel A).

The present identification of an MVP-specific Fab may allow for the construction of plasmids for functional knock-out purposes.

The hubs in our network (Table 1) thus represent attractive candidates for Chip-seq analysis, functional knock-down studies and regulon engineering.

The Wnt target gene Lgr5 is a putative stem cell marker based upon its crypt mRNA localization and a functional knock-in reporter experiment[ 8].

The first one is based on RNA-mediated interference (RNAi) where "functional knock-outs" of a particular gene can be studied and phenotypes identified.

The recent development of short interfering RNA (siRNA) technology based on RNA interference (RNAi) enables the functional knock down of all genes in a systematic manner.

In cases of family-specific mutations, supporting data from zebrafish functional (knock-down) experiments for genes such as MARS was obtained.

Protein functional knock-out by immunoneutralization of circulating EPO is a novel way of inducing EPO deficiency in live, active mice [ 27].