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Yet, despite the functional juxtaposition of insulin and glucagon, pancreatic beta and alpha cells derive from a common progenitor population that during embryonic development is first uniquely defined by the expression of the basic helix-loop-helix transcription factor neurogenin 3 (Neurog3) [ 1].
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The diversity of properties associated with these materials reflects the chemical composition, which allows variations in covalency, geometry and oxidation states, and the crystalline architecture, which may provide different pore structures, coordination sites, or juxtapositions of functional groups.
We could identify some variations in juxtapositions to crucial functional domains, especially in seroconverter sequences, when comparing them with others.
Furthermore, typically recurrent gene fusions characterized in cancers represent gain-of-function events arising from the juxtaposition of cell-type or lineage-specific regulatory elements and proto-oncogenes, or novel combinations of functional domains derived from two proteins that provide combinatorial or additive functionalities to normal genes.
For pain outcomes, the nonrandomized study on acute LBP found no effect of expectation, in juxtaposition to the effect on functional disability [ 6].
We also investigated the structural and functional consequences associated with the t(15 19 -mediated juxtaposition of Brd4 to Nut.
In consequence, we argue that the juxtaposition of contemporary emotionologies and social functional accounts of emotions suggests that the former potentially have overridden the latter.
Environmental gene censuses provide a coarse overview of the genetic potential within a given ecosystem and, by juxtaposition of distinct datasets, can reveal interesting taxonomic and functional aspects of particular habitats.
MAMs have been recently described as lipid raft-like domains that orient proteins to promote the ER-mitochondria juxtaposition; consequently, alterations in their composition may profoundly affect the physical and functional inter-organelle crosstalk.
This kind of functional epidemiology is likely to explain not only the genome level, descriptive, host-pathogen associations, but also the global juxtaposition of pathogen and host variations with a prospective impact on our understanding of pathogen/infection biology.
The juxtapositioning of CBP-containing nuclear bodies near the nuclear membrane is of interest given recent findings of functional interactions between CBP, nucleoporins and nuclear transport proteins [17,18].
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