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These scaffolds serve as templates for the formation of endothelial tubes that can be perfused; whether such microvascular structures are stable and/or functional is largely unknown.
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Its function is largely unknown.
Splice variants possessing the exon-5-encoded motif at the amino-terminal domain (ATD) of the GluN1 subunit are known to display robustly altered deactivation rates and pH sensitivity, but the underlying mechanism for this functional modification is largely unknown.
FAM164A is a hypothetical protein encoded in the reverse direction to IL7 and its functional importance is largely unknown.[24] The susceptibility region on chromosome 12 was previously linked with the expression of FAM119B.[20] We feel that the relationship of all three major susceptibility SNPs with the expression of TSFM suggests this as a strong candidate.
Its functional characterization is largely unknown.
However, the mechanism underlying the overexpression of CD11a and its functional consequences in SSc is largely unknown and remains to be elucidated.
Microarray experiments (Loop et al., 2004) and transcriptional target identification have identified lists of potential maintenance and differentiation regulators, but the functional relevance of these is largely unknown (Choksi et al., 2006; Southall and Brand, 2009).
If the system is largely unknown, functional connectivity approaches are useful because they can be applied in an exploratory fashion (Stephan, 2004).
Furthermore the impact of genotypic variation on early life microbial colonization in relation to the functional development of the gut is largely unknown.
How these two key functional properties of ESCs are maintained is largely unknown.
However, the functional neuroanatomy of body dissatisfaction in AN is largely unknown.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com