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The role of Nef in anti-apoptotic function is due to functional interaction with ASK-1 which links both the Fas- and the TNFR- mediated signals (by Fas ligand and TNFα) to the downstream JNK/p38 pathway [6], [24].
It would be promising to investigate the function of pTyr142 during meiosis and its functional interaction with γH2AX.
We consider NM attachment regions of DNA and discuss their characteristics and potential function before reviewing data that deal specifically with functional interaction with DNA replication factors.
This suggests that PML-RARα may hijack physiological functions of PML and RARα toward a new functional interaction with HIF-1α.
In experiments with transgenic Drosophila embryos, this function of the PTS restricts an enhancer to a functional interaction with only one promoter when two are present in the same transgene [45].
Here, we engineer FRP variants with defined oligomeric states and scrutinize their functional interaction with OCP.
In this study we investigated the role of TTC9A on anxiety-like behavior through its functional interaction with estrogen using the TTC9A−/− mice model.
We engineered a stable Rca hexamer ring and analyzed its functional interaction with Rubisco.
Thus, hRCE1 has important functional interaction with the P2′ and P3′ substrate positions in addition to the farnesylated cysteine at the scissile bond site.
As for Dkk1, a biochemical or at least functional interaction with Lrp6 has been demonstrated for Dkk2 and -4, in contrast to Dkk3, which neither binds Lrp6 nor significantly affects Wnt signaling (Brott and Sokol, 2002; Li et al., 2002; Mao and Niehrs, 2003).
All Sx isoforms shifted considerably the Cav1.2 normalized current, confirming functional interaction with Cav1.2 (Fig. 6B).
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