Sentence examples for functional instances from inspiring English sources

The function of linear motifs strongly depends on the context, e.g. functional instances mainly occur inside flexible regions that are accessible for interaction.

It has previously been shown that functional instances of protein motifs tend to lie in intrinsically disordered regions of protein sequence [12], [13], [14].

Additionally, conservation of LMs in closely and distantly related proteins has been used to improve the identification of functional instances of known LM patterns [11], [21], [22], [23].

Conservation patterns of regions flanking 116 LM functional instances were examined in relation to the presence/absence of the LM inside protein families.

Although the functional instances are enriched in the test sequences compared with control sequences, some functional instances may be present in the control sequences, because of possible false negatives in ChIP data.

The majority of these interfaces are likely to be true negatives, however, since our knowledge of SLiMs and PPIs is incomplete, this set will undoubtedly contain functional instances and true interactions.

Installation is simple, and a fully functional instance can be created quickly, even by novice users.

Because we can assume that non-functional instances of the word are not affected by the ChIP procedure, their counts are equal in the test and control sets of sequences: NT W pi ) = NC W pi ).

Given an instance of a smilesmolecule, this service enumerates functional group instances (from a predefined collection) occurring in the input molecule through an upper-level ontology has proper part predicate and produces a semantic equivalent of a chemical fingerprint in the annotatedsmilesmolecule output class.

For this purpose, one may use an extension of the described atom-centric fingerprinting procedure by typing atom and functional group instances to the generic classes of atoms and functional groups they instantiate.

The resultant specification of reactions and chemical entities enables simple, yet powerful SPARQL-based queries, e.g. to find the potential reactions of a given molecule and identify the atoms and functional group instances involved in these reactions (Appendix 11).