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Functional insights – Evidence strongly suggests that DNAJB6-myopathy mutations are gain-of-deleterious-function mutations.
Recent studies have revealed many structural and functional insights into replisome action.
By relating physiology to psychophysics, the model provides new functional insights and predictions about laminar cortical architecture.
The component features "learned" by successful models can provide functional insights into the systems underlying chromosome structure.
Our findings provide the structural and functional insights into EV71 2ando and establish a framework for structure-based inhibitor design.
In the field of G protein coupled receptors (GPCRs), the combination of in silico methods and pharmacological experiments represent a strong alliance for novel functional insights.
In summary, we obtained novel functional insights into the cell biological link of the AAA ATPases RUVBL1 and RUVBL2 to primary cilia.
A recent high-resolution structure of an active fungal PRC2 subcomplex has provided important mechanistic and functional insights into PRC2 activity and regulation.
Together with kinetochore protein counts [2, 3], these localizations predict the 3D protein architecture of a metaphase kinetochore-microtubule attachment and provide new functional insights.
These vectors can then be plugged into off-the-shelf machine learning methods to derive functional insights about genes or proteins.
Furthermore, the isolation of antibodies directed against antigens of importance in health, disease and developmental processes, has yielded a plethora of structural and functional insights.
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