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Because the AKIN criteria take into account even small changes in biochemical and functional indexes of kidney function, they are a more robust measure of AKI than cutoff values for serum creatinine level alone.
Effects of diabetes on cardiac function were characterized, inter alia, by substantive impairment of functional indexes including LVEF, CO/LVM (a measure of myocardial efficiency [ 30, 33]), LVEDV/LVM, LVESV/LVM, stroke volume/LVM and elevated LVM/BW (the latter a measure of relative LV hypertrophy).
To monitor the major cardiac functional indexes, we used serial echocardiographies.
Secondary efficacy endpoints included SLEDAI score, lupus serologic changes, systemic evaluations such as renal functional indexes, and hematological involvement.
The β-cell functional indexes HOMA-β and AIRins showed that the remission group preserved more β-cell function before IT.
The primary efficacy outcome variables were the changes from baseline to post-intervention assessments in the WOMAC, and Lequesne's functional indexes and joint space width.
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Baseline assessment included questionnaires to assess disease activity (Bath ankylosing spondylitis disease activity index (BASDAI)), function (Bath ankylosing spondylitis functional index (BASFI)) and well-being (BAS-G).
Physical function was assessed by Bath Ankylosing Spondylitis Functional Index (BASFI; on a scale of 0 10) [ 9].
Patient-reported physical function was measured with the Bath Ankylosing Spondylitis Functional Index (BASFI).
The functional or symptomatic status of OA patients was classified as functionally or symptomatically good (Lequesne's functional index = 10) or poor (Lequesne's functional index > 10; Table 1).
Physical function was assessed using the Bath Ankylosing Spondylitis Functional Index (BASFI; on a scale of 0 to 10).
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