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Because of their ability to conduct 'leak' currents, we reasoned that K2P channels such as K2P2.1 (KCNK2/TREK-1) might be functional in this system.
Our demonstration that the TRV 16K protein also is able to interfere with RNAi in Drosophila cells, leads us to suggest that many other plant virus silencing suppressor proteins are likely to be functional in this system.
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Although low levels of ATPase activity were associated with the proteoliposomes, it is possible that either MsbA was not reconstituted in a functional manner in this system or some other factor required for phospholipid translocation was lacking.
Although cortisol is known to be a key mediator of the stress response in humans, there are dramatic functional changes in this system across the course of pregnancy, with a 2 4-fold increase in maternal cortisol by full term.
Although these bacterial substrates target proteins that control host cell secretory traffic, most of the IDTS are dispensable for replication vacuole formation, indicating that there may be considerable functional redundancy in this system (Luo and Isberg, 2004).
Accumulation of SUMO-1-bound I κB α is also detected downstream of adenosine signalling during hypoxia and reoxigenation (Liu et al, 2009), although its functional contribution in this system is unknown.
New employees may need a year or more to become fully functional in the system.
TGF-β, however, remains a credible candidate for the functional Treg product in this system, with respect to both the induction and survival of Treg 63, and the down-modulation of effector T cell populations 64.
In the brain, the total levels of GC and ceramide were not affected by IFG, and, therefore, the IL-6 pathway does not appear functional in this in vivo system.
A functional in vitro system demonstrating this connection would enable the understanding of feedback by the integration of sensory input into the spinal reflex arc.
We use the 'Moodle' platform as the foundation to develop the service learning system, and add some functional modules in this learning system to help students learning effectively, such as Instant-Message Platform, learning materials, discussion forum, audio-visual media etc.
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