Inspecting genome databases and expression arrays (of an enzyme, transporter, receptor or ligand) without their integrative functional knowledge with respect to various forms of arthritis will be a starting point for functional genomics in this area.
ASD may involve disrupted functional segregation in this area, which may induce abnormal behaviors in patients.
The altered functional connectivity in this area in autism is of great interest, for some of the key typical symptoms of autism spectrum disorder are face processing and especially face expression processing deficits (Lai et al., 2014), which will impair social and emotional communication (Rolls, 2014).
In patients with left TLE we found a significant negative correlation with postoperative verbal learning scores in the left posterior hippocampus (P = 0.02), characterized by greater post- than preoperative functional MRI activation in this area being correlated with worse verbal memory performance (Fig. 4).
Beside the intrinsic mathematical interest (often related to functional equations) the results in this area are helpful for probabilistic and statistical modelling, especially in engineering and biostatistical problems.
Identification of molecules that are specifically expressed in the prefrontal cortex will be useful for understanding the mechanisms underlying the functional specialization of neurons in this area.
Either through mutations of the genes themselves, or inactivation of this functional cascade through co-factors, we believe identification of the Chk2 – p53 axis as critical to anthracycline therapy response provides a functional clue for further investigations in this area.
Neck hypertonia, more than trunk or hip rigidity, proved to be closely related to the subjects' functional performance, suggesting that muscle tone in this area plays a critical role in the control of balance, mobility, and coordination.
2, 3 The results of the present study elucidating the etiologies of PCS, each etiology's characteristics and their relationships between functional outcomes are improving the understanding in this area.
Metabolomics has also enriched genome-wide association studies (GWAS) in this area by providing functional data.
