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For example, RNAse P is a ribozyme involved in the maturation of small noncoding RNAs whose phylogentically conserved core is functional in isolation, although with significantly decreased activity [ 13, 14].
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As previously noted [6], [9], analyses of eggshell coloration considering single functional hypotheses in isolation are insufficient.
Experimental observations have shown that enzymes operate within metabolic pathways, may form functional catalytic associations and, thus, do not function in isolation of one another.
Neither functions in isolation.
We're not working in isolation".
Working in isolation is pointless.
Sequence-based phylogeny suggests a close evolutionary relationship of LmLeuRSCP1 to GlLeuRSCP1 which has been verified to possess fully functional editing domain in isolation [ 31].
Although LmLeuRS is ~1100 residues long, the presence of a probable functional editing domain in isolation proves it to be a novel drug target and encourages experimental verification for its drug binding abilities.
This haplotype also carries minor alleles from two other SNPS, 489T and 1068A (Table 1, Figure 1), and analysis of the functional effects of each in isolation suggests that they contribute, in an additive way, to the increased receptor function observed with this haplotype [ 30, 43].
This cascade results in functional isolation of the spinal cord below the injury.
The long range excitatory connections were modeled in isolation as an isolated laterally connected functional architecture.
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