Finally, analysis of selective constraints supports the adaptive fixation of amino acid replacements after gene duplication mainly leading to GroEL3 and that this fixation affected functional sites involved in interaction with protein clients.
The total burden of cerebral pathologies, in interaction with structural and functional compensatory processes, also referred to as brain reserve or cognitive reserve (7), determine when cognitive dysfunction becomes clinically manifest.
This indicates that the functional groups present on the rice straw were involved in interaction with Cd2+ ions.
The stronger link between CtIP/RBBP8 and cancer, and specifically breast cancer, relies in its functional interaction with BRCA1 in DNA repair.
By means of transgenic complementation assays, we demonstrate that, despite having different conservation patterns, monocot and dicot MLO susceptibility genes are essentially conserved with respect to functional features having a role in interactions with PM fungi.
It is the responsiveness of the PI3Kα/Akt pathway to low nM ouabain concentrations that clearly implicates the α2-isoform in a functional interaction with PI3Kα resulting in prevention of the hypertrophy.
The role of BS I is yet undefined but is unlikely to be involved in interactions with the functional leptin receptor isoform.
We propose that functional complementarity of AM fungal taxa in interactions with pathogens could mimic, or even be the cause of, previously observed relationships between AM fungal diversity and plant productivity.
It has been proposed that the difference between the risk and the neutral haplotypes resides in interactions with other functional polymorphisms, such as the indel in exon 6, but this hypothesis lacks experimental support.
While the molecular details remain to be mapped and fully elucidated, what is clear is that the C-terminal region of δ-catenin is of primary importance in its functional interaction with GLTP.
