Functional studies in developing xenopus embryos have demonstrated the role of ROR2 in non-canonical Wnt pathways [8], [9].
Therefore, all functional studies in developing neurons were carried out in DGCs aging 21 to 29 dpi, hereafter the "young" group.
While compelling evidence links these genes to PCa pathogenesis, it is not known whether TWIST1, VAV3 or the tumor suppressor DKK3 may have a functional role in developing resistance to hormonal therapy.
These results suggested that PET with radioisotope labeled tracer is useful for functional studies in developing cell-based therapies.
Additionally, we present the expression patterns of 15 primer pairs targeting 14 commonly used reference genes that represent different functional classes in developing grape berries.
In this study, we found very high expression of miR-202 in gonads, which is in agreement with previous reports in Atlantic halibut [ 49] and rainbow trout [ 31], indicating possible functional conservation in developing gonads.
Many dipteran species, including house fly, have a dominant male-determining factor (M) that is thought to inhibit the splicing of tra into a functional isoform in developing male zygotes (Traut and Willhoeft 1990; Dübendorfer et al. 2002; Bopp et al. 2014).
Here we use TCN 213, a novel GluN2A-selective antagonist to identify the presence of this subunit in functional NMDA receptors in developing cortical neurones.
Our study took advantage of this selective antagonism by TCN 213 and allowed us to use a pharmacological approach to monitor directly changes in subunit composition in functional NMDA receptors in developing cortical neurones.
40 Also, it is speculated that frequent exposure to childhood infections is responsible for the low prevalence of functional bowel disorders in developing countries and that early colonisation may enable the intestinal epithelium to respond efficiently to antigenic challenge, which may result in a pronounced amelioration of gastro-intestinal symptoms after infections.
