Structural consequences of this quaternary polymorphism, as well as its functional implications for helicase activity, are discussed.
Such genetic diversity has functional implications for the immune response to viruses and generates population-based variations in HLA class I allele frequencies and KIR gene profiles.
The requisite information for understanding the design and operation principles of these microsystems as well as their functional implications for optical networking is provided.
The current knowledge about the functional organization of this network, its pharmacology and functional implications for human motor control are discussed in detail.
The conformational flexibility of the N-HEAT region may provide significant functional implications, for example, adopting different conformations for the interactions with various mTOR regulators (Kim et al., 2008; Wullschleger et al., 2006; Zoncu et al., 2011).
Root architecture has important functional implications for the timing and extent of soil water extraction, yet selection for root traits in wheat breeding programs has been largely limited due to the lack of suitable phenotyping methods.
It is not inconceivable that these alterations of the IL-1 and TNF receptors may have important functional implications for the development of hyperresponsiveness in inflammatory airway diseases like asthma.
However, two recent studies, reporting hundreds of pairs of genes that have remained linked in diverse metazoan species over hundreds of millions of years of evolution, suggest widespread functional implications for gene order.
An important change, which has profound functional implications for steroid activation of the GR, is the loss of the contact between Asn564 and the C11 hydroxyl on dexamethasone.
The re shaping of overlap in responses in the cortex may have functional implications for disorders such as focal hand dystonia [45].
Identifying the DRP-1β isoform in the brain of embryonic and young mice excluding the adult phase may have functional implications for our future understanding of why such domain modularity evolved in this family of death –inducing kinases.
