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We recently developed the FAST-NMR methodology to discover biochemical functions or functional hypotheses of proteins of unknown function by experimentally identifying ligand binding sites.
One important application of sequence similarity networks is using them to form general functional hypotheses for sequences whose molecular functions are unknown.
Based on these results, new functional hypotheses concerning the assembly and function of T6SS proteins are proposed.
This indicates the need for a careful analysis of gene function underlying GO annotations in formulating functional hypotheses for cotton genes.
We presented three well-supported lineage-specific groups of kinases that emerged from our analysis, supported by existing structural and functional data about related proteins, and inferred additional functional hypotheses and the mechanisms that might enable these functions.
'A Functional Approach of Female Homosexual Behavior in American Bison' By H. Vervaecke and colleagues We present data on female homosexual behavior in American bison and review functional hypotheses with regard to its occurrence...
Our results underscore the importance of testing functional hypotheses in evolutionarily appropriate environments.
Lastly, we put forward functional hypotheses with a view to setting these results against a background of forest tree ontogenesis in general.
Computational models can provide valuable insights into structure function relationships in ncRNAs and can aid in the development of functional hypotheses and experimental designs.
Taxon-specific studies are providing quantitative data that can be used to generate and test functional hypotheses relating to jaw mechanics and feeding behaviour.
A huge amount of scientific research, particularly in the fields of behavioral and evolutionary ecology, has focussed on testing these functional hypotheses (Danchin et al. 2008; Fox and Westneat 2010; Fox et al. 2001).
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