Furthermore since many protein domains carry information about biochemical function but not biological function, the current situation with respect to meaningful functional grouping of proteins is somewhat unsatisfactory.
Nevertheless, functionally important genes often organise into the same pathway of functional grouping.
Ketene, any of a class of organic compounds containing the functional grouping C=C=O; the most important member of the class being ketene itself, CH2=C=O, which is used in the manufacture of acetic anhydride and other industrial organic chemicals.
b Functional grouping of upregulated genes (i) and downregulated genes (ii) in Y-79 cells treated with NPs.
New stress-related genes of similar functional motifs were identified, reemphasizing the importance of functional grouping in the analysis of multiple gene expression profiles.
Here, the primary purpose of the research might not be chemical in nature but rather into perception, thus making the implementation of a targeted chemical database a costly overhead; therefore having this sort of functional grouping available in broader chemical knowledge bases such as ChEBI is a large benefit.
When incorporating the temporal component of the transcriptional response and functional grouping of genes interesting patterns appeared.
These differentially regulated genes are shown in Figure 3, along-with their functional grouping and associated fold changes.
Functional grouping indicated that genes involved in inflammatory/immune signaling were the most enriched class of genes induced by miR-132 knockdown.
Functional grouping of genes whose expression were modulated by H19 RNA showed trends towards genes promoting cellular migration, angiogenesis and metastasis.
For each specific bait protein, nodes were organized by functional grouping with color indicative of the prevalence/frequency of the association: green (high), yellow (med), red (low), and blue (very low).
