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Such a degree of evolutionary conservation has, for example, been a powerful guide in sorting functional from non-functional DNA [ 8- 11] and to assign putative gene function.
But "functional" from whose perspective?
Fully functional from the day the exhibition opened, the architects would appreciate these improvisations.
These might include accurate and functional "from" lines, so that when you click "reply" to a piece of commercial e-mail you would actually be able to contact the person who sent it.
A magnate for reggae, it was fully functional from late 1968, by which time the Chin family had moved to the relative tranquillity of Jack's Hill on Kingston's northern outskirts.
Across the street, Hudson Beach Glass, which occupies a beautifully renovated former firehouse, features handmade art glass, both sculptural and functional — from undulating bowls and elaborate light fixtures to jewelry and mobiles.
They're functional from an IT perspective, but still using the older UI.
Discriminating functional from structural SAKI at the bedside, however, remains challenging.
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HEK293 cells were transfected with wild-type human P2X7 receptor or site-directed mutant constructs (K193A, K311A and E496A) known to be non-functional from measurements of barium/ethidium influx in the presence of ATP or 2′,3′-O- 4-benzoylbenzoyl -ATP.
Perry claims that one of his clients lost both his arms and has been in and out of the hospital "all summer" to treat infections; another victim lost part of his face and is non-functional from post-traumatic stress disorder (PTSD); one woman has breathing problems from scars in her lungs and must be cared after full-time by her husband, yet another victim.
Annotating and distinguishing the polymorphisms that render the protein non-functional from those that do not is essential for the study of disease-associated mutations.
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