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Maier's goal as a designer is to strip away all unnecessary parts until a dress or a shirt or a bag or a watch has been reduced to its functional essence — until it achieves what he calls "a certain nothingness".
If this reply is successful (for an updated version of this reply and a new related thought experiment, see Tye 2006), what it shows is that the property of having some phenomenal character or other has a functional essence.
This model captures the functional essence of histone marks as molecular signals that need not only to be 'written' but also to be 'read' by the appropriate machinery.
For many (most?) of the hemilineages one may be able to distill the functional essence of each unit down to one or two sets of cellular characteristics that may reflect the ancestral roles of these cells before the neuronal numbers were expanded.
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But if this is a real metaphysical possibility, then qualia do not have functional essences.
On this view, certain functional essences have a unifying role: these essences are responsible for the fact that material parts constitute a new individual, rather than just a lump of stuff or a collection of particles.
This approach leads us to identify structural domains and putative functions for about 20%% of the families with no structural or functional information, in essence, De-DUFing the DUFs and, in many cases, can also lead to the identification of critical amino acid residues responsible for protein function.
In essence, functional hemodynamic monitoring, though profoundly insightful in its values, is only another parameter that needs to be integrated into the greater view of patient care if its use is to realize its full potential.
In essence, the functional interactions of the filovirus-VP35-like NIRVs with viral products remain unknown.
In essence, the functional role of sHSPs would be avoiding aggregation of misfolded and/or unstable proteins even in the absence of stress.
In essence, this functional is a measure of distance between the given set { G j } and the supertree S. Different approaches to measure this distance are known.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com