Sentence examples for functional envelope from inspiring English sources

Such results are used in the design of vehicle components such as couplers and gangways or railroad functional envelope studies.

They were then cloned into an HIV-1 NL4-3-based vector that is deficient in the expression of a functional envelope (Env) protein and contains the Renilla luciferase gene in the position of nef [34].

Both Luc and CAT-reporter viruses were produced by transfection of 293T cells; the CAT-reporter virus was pseudotyped with the vesicular stomatitis virus envelope glycoprotein (VSV-G) to provide a functional envelope.

Moreover, a detailed structure of the complete functional envelope trimer is unknown [32], [54], [55], [56], [57], thus characterization of rare natural variants is an important source of relevant information on envelope structure/function.

This was expected since endogenous retroviruses reflect past exogenous retroviral infections and are a large (2 to 8%) component of the human genome [31], with 950 full length reverse transcriptase (RT) [32] and 16 candidate genes potentially encoding functional Envelope (Env) proteins.

Thus, a functional envelope protein must be incorporated in the Sendai-GP64 pseudotyped virions.

We present SQUID, a method for system identification in which the space of potential models is defined by a semi-quantitative differential equation (SQDE): qualitative and monotonic function constraints as well as numerical intervals and functional envelopes bound the set of possible models.

LTR retrotransposons are human endogenous retroviruses (HERVs) that have an intracellular existence as a result of a non-functional envelope gene.

We previously reported that an octaarginine (R8 -modified tetR8 -modifiedmultetra-lamellarenvelope-type nano device (R8-T-MEND) increases transfection efficiency in dendritic cell cultures (JAWS II).

The antibodies recognize a glycan-dependent epitope on the prefusion conformation of gp41 and unambiguously distinguish cleaved from uncleaved Env trimers, an important property given increasing evidence that cleavage is required for vaccine candidates that seek to mimic the functional HIV envelope spike.

Importantly, in contrast to RT-qPCR results, retroviral particles without any functional (fusogenic) envelope did not promote luciferase expression.