Sentence examples for functional endpoint from inspiring English sources

For example, visual field loss can be used as a functional endpoint; however, it occurs slowly and may require many years before meaningful changes occur.

Non-invasive positron emission tomography (PET) imaging with the fluorine-18 labeled glucose analog 2-fluoro-2-deoxy-D-glucose ([18F] FDG) is being used as a functional endpoint in phase I to III clinical trials in oncology for assessing therapeutic response, in addition to conventional endpoints such as toxicity in tumor size.

Positron emission tomography (PET) imaging with the fluorine-18 labeled glucose analog 2-fluoro-2-deoxy-D-glucose ([18 F]FDG-PET) is increasingly being included as a new functional endpoint in phase I to III clinical trials in oncology, in addition to conventional endpoints such as toxicity and decreases in tumor size.

The present study was designed to probe the phenomenon of functional selectivity at the D1 receptor further by testing the hypothesis that structurally dissimilar agonists with efficacies at these endpoints that equal or exceed those of dopamine would differ in ability to influence receptor fate after internalization, a functional endpoint largely unexplored for the D1 receptor.

We conclude that the TST can be used to estimate the functional endpoint of regeneration.

Finally, improvement in body iron stores, decrease in anemia and improvement in growth points towards a global improvement in child's health - a functional endpoint of multiple metabolic processes.

Lower levels of quadriceps femoris muscle (QFM) strength and function prior to total knee arthroplasty (TKA) result in lower functional endpoints after surgery [ 3].

Our findings highlight the need to integrate multiple, diverse, and functional endpoints to more appropriately discern the effects of Hsp90 inhibition upon HIF function.

The choice of suitable functional endpoints in glaucoma trials is also a critical consideration.

The aim is to measure whether the GM plant, it's intended (or perhaps anticipated unintended) use, or the transgene product can affect structural or functional endpoints.

This approach is already proposed for the assessment of soil quality, e.g. in the Netherlands (BISQ), where both structural and functional endpoints are utilized for various organism groups [52].