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Interestingly, rs9461045, one of these two markers, has a functional effect on the expression of KIAA0319 (29).
In the vast majority of mutations, there is no functional effect on the influenza virus itself.
However, there is no a systematic review about delivery of therapeutic ions and drugs/growth factors from MBG for the functional effect on the tissue regeneration despite that significant progress has been achieved in the past five years.
The analysis of the sequences did not evidence new mutations with a functional effect on the development of disease.
So far, a major functional effect on the NF-κB pathway has only be shown for the p.Leu1007fsX1008 variant 6.
However, a rare promoter variant, which exerts a significant functional effect on the ghrelin receptor transcription, showed partial co-segregation with obesity and overweight when examined in 2 pedigrees of whites.
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Building on this, we tested whether common LPA species present in blood (16:0, 18 1, and 18 2) have functional effects on the carotid body output using an en bloc perfused carotid body preparation (Fig. 1c 33,38.
To fully understand this process it is necessary to improve our knowledge on its molecular basis, from the binding sites to the signalling pathways that derive in structural and functional effects on the ion channel.
Cells and tissues transplanted into the adult brain or spinal cord have been shown to exert functional effects on the behavior of host animals in a variety of model systems, as well as in patients with neurodegenerative disease.
A possibility still remains, however, that the cell body has active conductances to exert functional effects on the synaptic integration in the dendrite.
Several single nucleotide polymorphisms within genes which comprise the fibrinolytic system have been shown to have functional effects on the rate of blood clot degradation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com