Suggestions(1)
Exact(8)
A functional driver cockpit is still in place (steering wheel, brake/acceleration pedal, etc).
In breast cancer 1q gain is commonly observed across all subtypes, however the functional driver in this region has yet to be elucidated.
A common strategy to distinguish functional, driver aberrations from such random, passenger events is to identify recurrent aberrations shared by multiple samples (Rueda and Diaz-Uriarte, 2010).
Of the 13 high confidence Pegasus predictions, 6 are recurrent in TCGA data suggesting a potential functional driver role in GBM tumorgenesis [ 39].
Whether E2F3 activity is a functional driver of metastatic progression or simply a marker for more aggressive disease is not yet clear.
Therefore, distinguishing the functional driver mutations, driver pathways or core modules from random passengers will be a crucial step in understanding the molecular mechanisms of carcinogenesis, which can further aid in effective diagnosis, treatment and prognosis of cancer patients.
Similar(52)
Genome-wide integrative approaches identify functional drivers of the disease and predict their specific regulatory functions.
The case study investigates the design motivations and functional drivers of a micro injection moulding machine.
A long-term trend in vegetation dynamics is apparent, wherein species that abound later in succession are the functional drivers, loading the environment with fuel for fires.
Long-term dynamics are apparent in systems in which the most prevalent species later in succession are the functional drivers of ecosystem disturbance (i.e. by providing fuel for fires).
Human mitochondrial DNA does not demonstrate such intra-strand parity, and we consider how its different functional drivers may relate to our theory.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com