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This loss of synapses may reflect functional downfall of astrocytes that are generally responsible for synaptic maintenance and homeostasis of ions and neurotransmitters, the latter being critical for synaptic transmission.
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"But we contributed to our own downfall.
Downfall 125.
That was my downfall".
A political downfall.
That was our downfall.
"Drugs were his downfall".
Our foibles become our downfall.
Economical, functional.
Functional clothes for functional living.
Tells about his recent downfall.
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