Sentence examples for functional dose from inspiring English sources

However, despite our knowledge on exposure levels in the environment (4), we do not know if neonicotinoids reach the insect brain at a functional dose that is capable of perturbing neuronal function.

In this perspective, we summarize current PTEN-targeting strategies and discuss potential approaches to modulate its functional dose, considering all stages of PTEN biogenesis from direct protein modulation to the targeting of relevant miRNAs as well as the PTEN gene and mRNA.

The functional dose in this study was 1.1 mg LT-B per 70-kg adult.

Reconstruction of the physiological functional dose of apoptotic protein in protein-deficient cells is a suggested strategy for cancer therapy.

A dose 10,000-fold lower than this functional dose is equivalent to 0.11 μg LT-B, which is our best estimate for a nonimmunogenic dose in humans.

USP7 also removes ubiquitin from p53 and the p53 E3 ubiquitin ligase MDM2 [ 34], therefore is a functional dose regulator of two important tumor suppressors.

The availability of adequate quantity of functional hematopoietic stem cells for functional dose-response is one of the major limitations of regenerative cell based therapy.

To test this expectation, we submitted An. gambiae larvae to acute toxicity assays in order to assess the shape and parameters of the functional dose-mortality response under exposure to increasing ammonia concentrations.

When attempting to interpret the ensuing microarray data, therefore, we could be confident that the cells received functional doses of both molecules.

Bioassays, used as pre-treatment tests for assessing functional doses for specific chemicals, and designed to detect increased tolerance towards chemicals before they result in treatment failures at salmon farms, are considered valuable tools in resistance management [ 88].

Although we attempted to individualize the functional exercise dose, it is possible that those with higher initial function were underworked.