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However, as the majority of genes are still hypothetical, a thorough examination for true functional discoveries will require biological experiments.
The database and the navigation tools are the basis for functional discoveries that span 350 million years of evolution of Arthropods.
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This is specially relevant if one is to consider the de-Novo functional discovery of the role of specific individuals or the reassurance of already envisioned hypothesis along the same lines.
This characterization of T-DNA insertions in mutants selected without regard to phenotype supports application of Agrobacterium-mediated transformation as an insertional mutagen for genome-based screens and functional discovery of genes in Histoplasma.
While such information can be obtained via a variety of approaches, this review describes the emerging use of synthetic biology to recombinantly reconstitute plant terpenoid biosynthetic pathways in heterologous host organisms as a functional discovery tool, with a particular focus on incorporation of the historically problematic cytochrome P450 mono-oxygenases.
The work should also be of interest to bioinformatics researchers who are interested in the use of functional domain-based analysis in evolutionary and functional discovery.
It should be noted that the functional discovery of these miRNAs was made mostly in cell culture systems, which may differ from the in vivo system.
Functional discovery of genes in potato is still a lengthy process and is often hampered by the complex characteristics associated with the potato genome, including autotetraploidy, self-incompatibility, and high heterozygosity.
Functional discovery is key.
DAVID promotes functional discovery through exploration of biochemical pathway maps, functional classification using GO terms and conserved protein domain architecture.
The first functional discovery of lectin, from seeds of Ricinus communis,was its ability to agglutinate red blood cells [ 4].
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