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The economic burden to society is remarkable with ensuing functional disablement.
It has been suggested that the functional disablement of NFkB following proteasome inhibition may affect intracellular signaling propagated through the mTOR pathway [ 48].
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Brief screening measures of cognitive functioning could be used to identify older adults with diabetes who are at increased risk for mortality and functional disability, as well as those who may benefit from interventions to prevent or minimize further disablement and declines in cognitive functioning.
Here again, bipolar disorder may incur particularly high disablement due to greater numbers of depressive episodes [ 20], higher functional impairment [ 21], and more prominent cognitive impairment or psychoses [ 22, 23].
In the Nagi model of disablement, functional limitation precedes disability [ 53].
It should not be assumed, however, that the severity of an impairment equates with severe functional limitation or disablement.
Disability, disablement, and impairment are universal.
Most individuals, at some point in their lives, will experience disability, disablement, or impairment.
Recovery from disablement: what functional abilities do rehabilitation professionals value the most?
In the disablement process, functional limitations immediately precede activity limitations [ 15].
Although health deteriorates along an ageing and disablement process, disability may be reduced through the effects of HAs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com