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Earlier work in vertebrate cells indicated that the functional diameter of the channel changes as cells progress through the cell cycle (Feldherr et al. 1984).
In vitro studies showed that LtxA formed voltage-gated ion channels of large conductance in the planar lipid bilayer, with an approximate functional diameter of 0.96 nm (Iwase et al., 1990; Lear et al., 1995;).
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However, studies of excised lungs employing micro-beads indicate that capillaries can retain functional diameters of ∼1.7 µm even under pressure conditions expected to completely collapse the capillary bed [48].
Demand is increasing for functional small-diameter vascular grafts (diameter < 6 mm) for clinical arterial replacement.
There is an increasing demand for functional small-diameter vascular grafts (diameter < 6 mm) to be used in clinical arterial replacement.
The fabrication of functional small diameter blood vessel analogs has implications in vascular disease treatment.
The significant enhancement of ECM expression and maturation, together with the pre-vascularization capacity makes this approach highly attractive in terms of generating functional small diameter TEBV devoid of any foreign material.
Morphological measurements for both femur and tibiotarsus include functional length, diameter and cortical cross-sectional area at the mid-diaphysis, curvature in both frontal and sagittal planes and torsion.
Tissue engineering offers an attractive approach to creating functional small-diameter (<5 mm) blood vessels by combining autologous cells with a natural and/or synthetic scaffold under suitable culture conditions, which results in a tubular construct that can be implanted in vivo.
More directly, L. Dall'Olmo et al. address the relevant issue to fabricate functional small-diameter vascular grafts, evaluating the potential of decellularized rat iliac arteries.
Table 4 Chart summarizes the typical imaging features of the different ovarian lesions Group Lesion Findings T2 T1 Gd-T1 Mean age Cystic unilocular Functional cysts follicles (diameter <20 mm), dominant follicles (diameter 20 25 mm), follicular cysts, corpus luteum cysts.
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