Sentence examples for functional depletion from inspiring English sources

This functional depletion indirectly supports our speculation about temporary cell function depletion.

If the Ap2aIREScre/+ COET associated phenotype is due to functional depletion of Smad1, then providing an additional source of Smad1 to the affected tissues may ameliorate the phenotype.

This phenocopy indicates functional depletion of endogenous CYK-4.

Finally, muscle and fat loss are only one aspect of functional depletion.

Similarly, the 1 mM glucose condition leads to a functional depletion of the LRP6 receptor without genetic manipulation.

As in Figures 3 and 6, functional depletion of MGRN1 led to elevated levels of LC3 II.

The kinetics of functional lubricant depletion shows that desorption is the main mechanism of lubricant depletion under rapid and isothermal heat treatment and is the major cause of lubricant thermal instability on the surface.

In functional studies, depletion of YY1 inhibited the clonogenicity, migration, invasion, and tumor formation of breast cancer cells, but did not affect the clonogenicity of nontumorigenic cells.

To validate functional MKL1/2 depletion, we examined the expression of the well established MKL/SRF target genes smooth muscle actin (SMA) and transgelin (SM22).

We do not know yet which of the MVI binding regions is involved in the association with AKAP9, but certainly this interaction is functional because depletion of MVI causes not only an increase of AKAP9 and PKA kinase expression levels but also a substantial increase in the cAMP level.

In functional studies, depletion of BAP1 protein in the 92.1 UM cell line using siRNAs led to a change in cell morphology from spindle to a more epithelioid phenotype, loss of melanocytic differentiation and transition from a 'class 1' to a 'class 2' gene expression profile (Harbour et al, 2010).