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Functional delivery of siRNA in mice using dendriworms.
Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, et al. Functional delivery of viral miRNAs via exosomes.
Functional delivery of oligonucleotides to epidermis in order to edit or modify expression of mutant genes.
Transfection reagents, such as cationic lipids and polymers, are commonly utilized to improve functional delivery of nucleic acids including oligonucleotides.
NC-loaded DMN offers great potential as a relatively low-cost functional delivery system for enhanced transdermal delivery of LMWH and other macromolecules.
When taken up by floxed reporter cells, exosomes containing WW-Cre were capable of inducing DNA recombination, indicating functional delivery of the protein to recipient cells.
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To improve treating efficacy, they are also developed into more functional drug delivery nanosystems.
We had constructed a mitochondrial-targeted functional nanoparticle delivery system for enhancing antitumor efficiency.
In addition, nanoparticles' drug loading capacity, colloidal stability, and interactions with loaded drugs are related to their physico-chemical properties and are important for a functional drug delivery device [4 6].
This suggests that gammaretroviruses should be re-evaluated as functional gene delivery tools for non-dividing cells.
This is a novel promising method for functional RNA delivery.
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