Sentence examples for functional death from inspiring English sources

TRAIL, either as a type II transmembrane protein or as a soluble protein, interacts with four different transmembrane receptors, namely TRAIL-R1 and TRAIL-R2 (which transmit apoptotic signals) and TRAIL-R3 and TRAIL-R4 (which lack a functional death domain and therefore function as decoy receptors to protect cells from apoptosis).

In the United Kingdom, the accepted criterion is brain stem death, or the "permanent functional death of the brain stem" (Pallis 1982).

Several TRAIL receptors have been identified: two of these receptors TRAIL-R1/DR4 and TRAIL-R2/DR5 contain cytoplasmic death domains and signal apoptosis, while two other decoy receptors, TRAIL-R3/DcR1 and TRAIL-R4/DcR2 lack a functional death domain and do not mediate apoptosis.

"I am committed to ensuring that Nebraska has a functional death penalty," Ricketts said in a statement, adding that "the Nebraska Department of Correctional Services has purchased the drugs necessary to carry out the death penalty here in our state".

Since TNFR2 lacks a functional death domain, only TNFR1 can initiate apoptosis.

DcR1 and DcR2 lack functional death domains and cannot mediate apoptosis.

Decoy receptor 2 (DcR2) possesses a truncated, non-functional death domain, whereas the third decoy receptor, osteoprotegerin is a secreted, soluble receptor (Ashkenazi and Dixit, 1998).

However, published experiences [ 32, 40, 41] demonstrate that patients can, and indeed appreciate to talk about personal and sensitive issues such as increasing functional decline, death, dying, and bereavement in repeated interviews over a longer period of time.

To assess the impact of clinical instability (CI) and delirium on admission to a rehabilitation unit on clinical and functional outcomes (death, transfer to acute care, poor functional recovery) at discharge, in a population of elderly patients.

The following variables were collected: patient's age and sex, fracture type (AO classification), haemoglobin levels (Hb) on admission and pre- and post-operatively, amount of pre- and post-operative blood transfusion, operation time, duration of hospital stay, intra- and post-operative complications, functional recovery, death rate and cost factors relating to the technique.

In addition, TRAIL also binds to the decoy receptors TRAIL-R3 (DcR1) and -R4 (DcR2), which lack a functional cytoplasmatic death domain and therefore cannot induce apoptosis.