Sentence examples for functional cycles from inspiring English sources

Open image in new window Figure 1 Schematic diagrams of functional cycles of ABC transporters.

Macromolecular machines, such as the ribosome, undergo large-scale conformational changes during their functional cycles.

Although their mode of action is often compared to that of mechanical machines, a crucial difference is that, at the molecular dimension, thermodynamic effects dominate functional cycles, with proteins fluctuating stochastically between functional states defined by energetic minima on an energy landscape.

Biological macromolecules and their complexes often undergo large structural changes during their functional cycles [1], [2].

These systems exhibit large conformational changes during their functional cycles.

We believe that although proteins with GAP domains are generally viewed predominantly as functionally well-defined components of the GTPase functional cycle, at least some of them obviously have acquired additional functions besides facilitating GTP hydrolysis and thus "re-setting" or "erasing" a signal carried by a GTP-loaded or "active" GTPase.

These different states may relate to function when they are within the functional cycle, but they may also be due to differences in the experimental conditions under which the structures were solved, or could be due to natural or engineered mutations.

A King Altman diagram of the actomyosin functional cycle.

B Free-energy landscape of the actomyosin functional cycle.

A King Altman plot of the three-state functional cycle of AcrB.

Open image in new window Fig. 1 Schematic diagram of the actin myosin functional cycle.