As functional constraint, we specify that each user needs to be able to connect to at least one base station.
Lower levels of protein polymorphism and divergence in domains are consistent with higher functional constraint.
This configuration cannot be broken up without a loss of regulatory inputs and constitutes a functional constraint on genome rearrangement.
Its structural conservation over hundreds of millions of years arguably reflects a considerable degree of functional constraint.
A reasonable explanation is that the functional constraint on MEF2B is lower than on the other three MEF2 genes.
Three non-synonymous substitutions were detected (Table S1), but all at sites that appear to be under minimal functional constraint [38].
The limited variation for the nucLSU rRNA and mtSSU rRNA sequences is likely due to their functional constraint at the nucleotide sequence level.
The constrained sequence means the sequence under functional constraint.
Thus, we consider two different forms of functional constraint.
Thus, XXyac-R12DG2.2 is likely to be under functional constraint.
This could be indicative of a functional constraint.
