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Within different functional compartments there are also special proteins that perform different biological functions.
Extracellular glutamate: functional compartments operate in different concentration ranges.
Moussawi, K., Riegel, A., Nair, S. & Kalivas, P. W. Extracellular glutamate: functional compartments operate in different concentration ranges.
In mammalian cardiomyocytes, mitochondria and adjacent ATPases with participation of creatine kinase (CK) constitute functional compartments with an exchange of ADP and ATP delimited from cytosolic bulk solution.
The miniaturized genetic sample preparation system consisted of several functional compartments including cell purification, cell separation, cell lysis, solid phase DNA extraction, polymerase chain reaction and capillary electrophoresis.
Altogether, we propose that combinatorial lipid composition of the cytosolic leaflet of organelles not only defines the electrostatic territory but also distinguishes different functional compartments within this territory by specifying their varying surface charges.
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Our finding of a particulate or fibrous-like SAF-A staining pattern in the ANC of both active CTs and the Barr body supports a function of SAF-A for the structural organization of chromatin within this functional compartment.
It may also be a surprisingly plastic functional compartment, with recent data showing not only that the AIS can disassemble rapidly following cellular injury [60], but also that the structure can relocate along the axon [37], or change its length [78] in response to long-term changes in electrical activity.
Such coupling could extend the size of a functional compartment from a single cell to a multi-cellular syncytium, acting as a functional network.
The possibility to control protein localization by two independent events can be exploited to sequester any protein of interest away from its functional compartment.
To measure the activity of the functional compartment of the spleen, 99mTc-labelled heat-altered autologous erythrocyte scintigraphy with quantification of spleen uptake seems the most appropriate technique.
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