Sentence examples for functional commitment from inspiring English sources

Thus, the developed cues, driving the functional commitment of ARPCs, offer a route to recreate the microenvironment of the stem cell niche in vitro, that may serve, in perspective, for the development of ARPC-based bioengineered devices.

Notably, morphological features provide information on the functional commitment of M/M [11-13] [11-13]

We observed restored Rex1GFP downregulation and functional commitment upon simultaneous knockdown of Pum1 and Tbx3.

Two-hybrid screens are sometimes referred to as functional screens, since interacting proteins might give a functional hint if at least one of the partners has a known functional commitment in a well understood signaling pathway.

The production of IL-12 by phagocytic mononuclear cells and dendritic cells is a key component of the molecular networks that induce functional commitment of naïve CD4 T lymphocytes to a Th1 proinflammatory phenotype [ 13- 15].

Bioinformatics analyses were performed to elucidate a correlation between structural disturbances and putative functional commitment, achieving a possible explanation for the pathogenic mechanism of the novel p.K23N missense mutation of HSF4.

Both strategies eliminated the delay in downregulation of Rex1 and rescued the functional deficiency in commitment.

In parallel, BMSPCs exposed to S1P demonstrated functional endothelial lineage commitment as demonstrated by 10-fold higher tube formation in matrigel assays (P < 0.05) and 4(f)).

Functional differences in commitment toward the cardiac phenotype was tested by comparing stimulus-induced Ca2+ release in differentiated CM- and CF-derived iPS cells and neonatal CMs, used as a reference.

Exhibit exceptional leadership performance, functional expertise, and a commitment to leading innovation.

Treg lineage commitment and functional stability are influenced by selected extracellular signals from the local environment, shaped by distinctive intracellular signaling network, and secured by their unique epigenetic profile.