Other genes are in functional clusters that carry out specialized functions, largely restricted to immune tissues.
About 45 functional clusters from the Biological Process and Molecular Function categories of the GO database were analyzed before subtraction and about 30 functional clusters were analyzed after subtraction and the results shown in radar graphs.
In order to identify the neurotransmitter phenotypes of functional clusters, we relied on the combination of transgenics as well as the use of the recent creation of open-access zebrafish larval brain atlases by several groups2,3,4,32.
Network analyses based on GO biological process revealed eight functional clusters among the 70 MSA genes including development, cell proliferation, metabolism, blood pressure and circulation, nervous system, double-strand DNA break repair, immunity and centrosome function (Fig. 2).
The genes related in terpene synthesis are usually found to be lined together, forming functional clusters in plants (Matsuba et al. 2013).
The functional clusters of TPS genes are already found in several species, such as Eucalpyus, solanum, Vitis vinifera, Arabidopsis, rice, etc. (Shimura et al. 2007).
The enzymes in these two functional clusters have different metals bound at their active sites.
These regions are formed by transposons or inverted duplications of functional clusters [4], [46], [47].
More clearly, the 13 overrepresented functional clusters confirm the main biological processes.
Numerous instances of genes that could not grouped in functional clusters also exhibited divergent behavior.
Due to significant relevance of BP, only functional clusters belonging to this category are presented in the current study.
