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This study evaluated the changes in IL-6 and IL-6 function associated accessory molecules by human fetal membranes to determine the functional availability of IL-6 assessment in an in vitro model of polybacterial infection.
A functional product is an integrated package consisting of hardware, software and a service support system that provides a customer with a certain function and is sold under a performance-based contract that includes a functional availability guarantee.
The organization has a strong influence on the functional availability of proteins and likely provides a molecular scaffold for more complex protein networks.
A previous paper by the authors described a simulation-driven development strategy for designing FP that are optimised for functional availability and support costs.
The resulting analysis gave an indication of a suitable guaranteed functional availability level for the product and could be used to compare the performance of different design options.
The Air Force is planning to replace several different satellite constellations in the 2020s, and the functional specifications for next-gen satellites will emphasize resilience rather than mere functional availability.
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Although many of the sites have been modified with success, the relative paucity of functional group availability within proteinogenic amino acids can sometimes leave open questions about specific functions of the metal binding ligands.
The system is completed by a high-affinity binding protein (CRF-BP), which acts as a decoy receptor and regulates functional peptide availability.
In addition to its role in functional genomics, availability of the yeast non-essential gene deletion array (yGDA, approximately 4700 strains) also provided the opportunity to investigate the cellular target sites of inhibitory compounds [ 5- 7].
Despite the ease of modern gene editing tools, analyses of overexpressed and/or tagged proteins frequently fail to recapitulate the endogenous protein characteristics, such as expression level, turnover, functional epitope availability and, as a consequence, their localization and dynamics (Huh et al., 2003; Swulius and Jensen, 2012; Khmelinskii et al., 2012).
On the other hand, both P rrn and P psbA are known to incorporate elements recognized by a bacterial-type, multi-subunit plastid-encoded polymerase (PEP), which also includes a nuclear-encoded sigma-factor [ 53, 54], suggesting a possible competition for a functional PEP availability between these promoters, and leading to increased aadA transcripts and reduced xynA transcripts.
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functional dissemination
functional readiness
professional availability
functional usability
technical availability
practical availability
functional provision
functional possibility
operational availability
functional capabilities
functional accessible
functionalities availability
practices availability
functioning availability
functionality availability
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