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The experimental work indicated that the main chromosome and the three smaller chromosomes (pHV4, pHV1, and pHV3) all contain functional autonomously replicating sequences (ARS).
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The recent discovery of these distinct and multipotent cell populations of the pilosebaceous unit provokes the question for their functional significance and if they function autonomously under physiological conditions during tissue homoeostasis.
A toxic nodule is a solitary, autonomously functioning thyroid nodule.
The organization of these forms and the identification of an autonomously replicating sequence functional in S. cerevisiae, strongly suggest that an extrachromosomal circular DNA (eccDNA) molecule serves as an intermediate in the amplification of the Z. bailii region in yeast genomes.
Once activated, however, the functional units tend to work autonomously without further external regulation [ 17].
Several lines of investigation now support a model whereby the epidermis is regionally compartmentalised into functional units that are maintained autonomously (Ghazizadeh and Taichman, 2001; Levy et al., 2005; Page et al., 2013).
The fully functional RNA replicon is able to replicate autonomously within each infected cell [ 41, 42].
The formation of viable seed in apomicts requires the formation of functional endosperm, and this occurs pseudogamously or autonomously, i.e. with or without fertilization of the ES central cell, respectively.
A team of researchers from Harvard and MIT have developed a new kind of robot - one that's capable of autonomously folding itself up into particular functional shapes and then going about its tasks.
The much lower adhesion mediated by the 5-repeat DC-SIGNR might at first be unexpected, since the CRDs fold autonomously and appear to be fully functional based on solution binding data and on affinity purification.
A recent functional assay based on plasmid maintenance identified a set of 84 autonomously replicating sequences (ARS) in the genome of L. kluyveri (Liachko et al. 2011).
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