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Current theories posit that executive function deficits account for many of the poor outcomes in ADHD, which are supported by evidence of delayed maturation and functional anomalies in the prefrontal-striatal circuitry that underpin executive functioning.
Taken together, our data revealed that the antioxidant catalase counteracts against high fat diet-induced cardiac geometric and functional anomalies possibly via an IKKβ-AMPK-dependent restoration of myocardial autophagy.
Although past investigations have shown that the cell cycle machinery can be reactivated in TD cells, much as it is in reversibly quiescent ones [17], [27], subtle functional anomalies might have escaped detection.
This view is supported by single-cell recordings in non-human primates [31], [32], [33], by neuroimaging studies in humans [34], [35], [36] and by individuals with autism who show anatomical and functional anomalies in the STS region [37].
These inclusion/exclusion criteria sought to remove confounding effects of (1&2) age- or drug-related hypometabolism in the brain, (3) structural and functional anomalies due to illness or injury, (4) differences in psychological health, and (5) differences in linguistic processing.
These functional anomalies involve several organs controlled by common neuronal networks located in the brainstem.
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Asic3 −/− mice showed subtle cardiovascular changes at baseline condition, with no obviously structural or functional anomaly and only lower ratios of LF power spectral density than Asic3 +/+ mice.
Moreover, moderate ventriculomegaly (with a size between 10 and 15 mm) may be a type of functional anomaly that sometimes regresses during pregnancy [ 40, 41].
We successfully employed the Gini Importance measure derived from Random Forests to identify discriminative functional connectivity anomalies induced by schizophrenia.
The inclusion criteria were a confirmed diagnosis of HF based on clinical criteria plus a structural and/or functional heart anomaly according to echocardiography, following the diagnostic criteria for HF proposed by the European Society of Cardiology [ 23].
Thus, both structural changes and differences in ion channel kinetics together create optimal proarrhythmic conditions, and the disease can be regarded as a combination of a structural cardiomyopathy in conjunction with a functional channel anomaly.
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