We identified important regulatory networks and functional categories pertinent to these genes, and performed an extensive survey of literature to find experimental evidence that support the synthetic lethality relationships between the genes identified and p53.
Although deregulation of the Sprouty genes can indicate a general aspect of the Sprouty status in a given cancer, this needs to be interpreted in relation to the gene expression at the protein level and pertinent functional outcomes.
Further, we identified important regulatory networks and functional categories pertinent to the candidate p53 synthetic lethal genes.
These results suggest that AVG playing may induce functional integration of insular subregions and pertinent networks therein.
These mutations were then mapped to the MSV3d database and pertinent structural, functional and evolutionary features were extracted and formalized as Prolog facts, as described in the Materials and Methods section.
Functional groups pertinent to nectary development and nectar production were then manually inspected and grouped based upon TAIR annotations [ 73] and literature searches.
The positive outcome of our immunogenetic study suggests that parameters such as adequate study population, sufficient statistical power, relevant cell type and pertinent biological read out are critical in discovering the functional impact of disease-associated SNPs.
Our study illustrates a pertinent approach utilizing both functional and positional criteria for selecting disease candidate genes.
Our experiment demonstrated the possibility to study pathophysiological associations between passivity symptoms and the function of the pertinent action monitoring network with both functional and behavioural data.
The image is shocking and pertinent.
Much more frequent and pertinent are the love declarations.
